Key result
Initiation of propranolol for infantile haemangioma in an ambulatory setting was safe, with 0 severe adverse events and asymptomatic decreases in heart rate (P<0.001) and systolic blood pressure.
Why the study?
Is propranolol initiation safe and well-tolerated in children with infantile haemangioma in an ambulatory day-care setting?
Cohort (n=220)
No
Is propranolol initiation safe and well-tolerated in children with infantile haemangioma in an ambulatory day-care setting?
Propranolol initiation up to 2 mg/kg/day for infantile haemangioma is safe and can be monitored in an ambulatory day-care setting without severe adverse events.
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May support ambulatory propranolol initiation for infantile haemangioma; leaves open need for prospective confirmation before practice change.
Fogel et al. (2018) conducted a cohort in infantile haemangioma (n=220). Propranolol was evaluated on severe treatment-related adverse events. Initiation of propranolol for infantile haemangioma in an ambulatory setting was safe, with 0 severe adverse events and asymptomatic decreases in heart rate (P<0.001) and systolic blood pressure.
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