Key result
High-intensity and competitive exercise is associated with early disease manifestation and an increased risk of malignant arrhythmias and sudden cardiac death in patients with ARVC/D.
Why the study?
Arrhythmogenic right ventricular cardiomyopathy/dysplasia carries risk of ventricular arrhythmia and sudden death, and high-intensity exercise is associated with adverse outcomes.
Does high-intensity exercise increase the risk of ventricular arrhythmias and disease progression in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia?
Does high-intensity exercise increase the risk of ventricular arrhythmias and disease progression in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia?
High-intensity exercise accelerates disease progression and increases the risk of malignant arrhythmias and sudden cardiac death in patients with ARVC/D, supporting exercise restriction.
Answers are grounded in this paper and cite their sources.
Exercise restriction integral to ARVC management; leaves open intensity thresholds for prospective validation.
Arrhythmogenic right ventricular cardiomyopathy/dysplasia is inherited cardiomyopathy that has a propensity for ventricular arrhythmia, ventricular dysfunction, and sudden cardiac death. High-intensity exercise is associated with early disease manifestation and increased risk of malignant arrhythmia and sudden death. Exercise restriction should be advised as an integral part of disease management. This overview summarizes the medical literature on the impact of exercise in triggering ventricular arrhythmias and disease progression.
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Kaddoura et al. (2022) conducted a review in Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D). High-intensity or competitive physical exercise vs. Inactive lifestyle or recreational/low-intensity exercise was evaluated. High-intensity and competitive exercise is associated with early disease manifestation and an increased risk of malignant arrhythmias and sudden cardiac death in patients with ARVC/D.
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