Key result
Mechanical thrombectomy successfully treats large-vessel stroke caused by cardiac papillary fibroelastoma.
Why the study?
Papillary fibroelastoma is typically an uncommon cause of large-vessel ischemic stroke despite having significant embolic potential.
Case Report (n=1)
No
Histopathologic examination of thrombectomy-retrieved emboli can successfully identify rare cardioembolic sources, such as papillary fibroelastoma, in young patients with cryptogenic stroke.
Histopathologic analysis of retrieved emboli may identify rare cardioembolic sources in young stroke patients; leaves open whether routine use improves diagnosis.
Papillary fibroelastoma (PFE) is a benign cardiac tumor that, despite having significant embolic potential, is typically an uncommon cause of large-vessel ischemic stroke. We report a 19-year-old female who presented with acute aphasia and right hemiplegia due to a left middle cerebral artery M1 occlusion and was successfully treated with mechanical thrombectomy. Histopathologic examination of the retrieved embolus established the diagnosis. This case underscores the diagnostic importance of pathological examination of thrombectomy specimens when identifying rare cardioembolic etiologies of cryptogenic stroke.
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Kim et al. (2026) conducted a case report in Large-vessel ischemic stroke due to papillary fibroelastoma (n=1). Mechanical thrombectomy was evaluated on Reperfusion status and neurological improvement. Mechanical thrombectomy successfully treated a large-vessel ischemic stroke caused by a papillary fibroelastoma in a 19-year-old female, with histopathologic confirmation from the retrieved embolus.
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