What is the clinical evidence from this study?

Study design: RCT. Population: Primary hypertension (n=300). Intervention: Daily SMS reminders vs. Standard pharmaceutical care. Primary outcome: Proportion of adherent patients (defined as MMAS-8 score ≥6 and pill count rate ≥80%).

July 18, 2017TrialsOpen Access

The effectiveness of daily SMS reminders in pharmaceutical care of older adults on improving patients’ adherence to antihypertensive medication (SPPA): study protocol for a randomized controlled trial

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Key result

Daily SMS reminders of antihypertensive medication intake will be evaluated in a planned randomized controlled trial to determine their effect on medication adherence in older adults.

Why the study?

Does daily SMS reminders in addition to standard pharmaceutical care improve medication adherence in older hypertensive ambulatory patients?

Study Design

Type

RCT (n=300)

Blinding

Single-blind

Randomization

Simple randomization stratified by gender

Multicenter

Yes

Structured PICO

Does daily SMS reminders in addition to standard pharmaceutical care improve medication adherence in older hypertensive ambulatory patients?

Population

300 planned older ambulatory patients (aged ≥55 years) with primary hypertension on antihypertensive treatment for at least one year, to be followed for 3 months.

Intervention

Daily personalized SMS reminders of antihypertensive medication intake provided by pharmacists in addition to standard pharmaceutical care for 3 months.

Comparator

Standard pharmaceutical care only, plus a welcome SMS and an end-of-trial SMS.

Outcome

Combined adherence endpoint consisting of subjective self-reported medication adherence via the eight-item Morisky Medication Adherence Scale (MMAS-8) and objective pill count rate at 3 months.composite

This study protocol outlines a pragmatic RCT to evaluate whether daily SMS reminders can improve adherence to antihypertensive medication and blood pressure control in older adults.

Limitations

Sample size lacks statistical power to detect significant change in systolic blood pressure.
Not designed to focus on cardiovascular risk reduction, prevention of cardiovascular events, or overall cardiovascular mortality.
Addresses only unintentional non-adherence due to forgetfulness, not intentional non-adherence.
Relies on patient-reported health and medication history.
Pill count assessment may be biased if patients remove pills before visits.
Three-month intervention period is relatively short to ensure long-lasting clinical improvement.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

SMS reminders for antihypertensive adherence lack proven benefit in older adults; the planned RCT will provide needed evidence.

Cite This Study

Haramiova et al. (2017) conducted an RCT in Primary hypertension (n=300). Daily SMS reminders vs. Standard pharmaceutical care was evaluated on Proportion of adherent patients (defined as MMAS-8 score ≥6 and pill count rate ≥80%). Daily SMS reminders of antihypertensive medication intake will be evaluated in a planned randomized controlled trial to determine their effect on medication adherence in older adults.

synapsesocial.com/papers/6a74660bc2eb6969bf093901 https://doi.org/10.1186/s13063-017-2063-8

Topics

Hypertension management

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The effectiveness of daily SMS reminders in pharmaceutical care of older adults on improving patients’ adherence to antihypertensive medication (SPPA): study protocol for a randomized controlled trial

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Topics

The effectiveness of daily SMS reminders in pharmaceutical care of older adults on improving patients’ adherence to antihypertensive medication (SPPA): study protocol for a randomized controlled trial

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider