Answers are grounded in this paper and cite their sources.
A short and modular synthetic pathway using intramolecular 1,3-dipolar cycloaddition reactions and yielding functionalized isoxazoles, isoxazolines, and isoxazolidines is described. The change in shape of previous compounds and those in this study is quantified and compared using principal moment-of-inertia shape analysis.
No takes yet. Share an insight, caveat, or question.
Muncipinto et al. (2010) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: