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Limit for humans of 50-70 population doublings before programmed senescence and cell death. While there has been a virtual explosion of papers detailing the attributes of various forms of telomerase-negative stem cells in the field of regenerative medicine, relatively few papers have been published with respect to telomerase-positive stem cells. The following is a review of work detailing the basic science characterization of telomerase-positive stem cells as well as their use in regenerative medicine.
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Young et al. (2020) studied this question.
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