January 1, 2007Health Affairs249 citations
View Full PaperAdvances In The Prevention And Treatment Of Cardiovascular Disease
Key Result
Over the past thirty-five years, advances in the prevention, diagnosis, and treatment of cardiovascular conditions have contributed to a 50 percent decline in U.S. age-adjusted cardiovascular mortality.
PICO
P
Population
Cardiovascular disease
E
Exposure / Comparator
Advances in prevention, diagnosis, and treatment
O
Primary Outcome
Age-adjusted mortality from cardiovascular disease
Abstract
Over the past thirty-five years, U.S. age-adjusted mortality from cardiovascular disease declined 50 percent. This marked reduction reflects advances in the prevention, diagnosis, and treatment of common cardiovascular conditions. Pharmaceutical agents play a major role in prevention of atherosclerosis and its consequences: heart attack, stroke, and heart failure. Additionally, novel device-based therapies contribute to the decline in cardiac morbidity and mortality. Whereas innovative strategies based on accurate imaging of the heart and blood vessels are implemented widely now, hope exists that lifestyle changes, early risk-factor screening, and more efficacious drugs will strikingly reduce cardiovascular disease in the future.