Key result
The 2013-2014 military and political conflict in the Central African Republic was associated with a 57% and 36% decrease in acute flaccid paralysis surveillance activity compared with previous years.
Why the study?
How did the military and political conflict in the Central African Republic affect the epidemiological surveillance of poliomyelitis in 2013 and 2014?
Observational
How did the military and political conflict in the Central African Republic affect the epidemiological surveillance of poliomyelitis in 2013 and 2014?
The military and political conflict in the Central African Republic severely disrupted acute flaccid paralysis surveillance and vaccination coverage in 2013 and 2014.
Conflict may sharply impair AFP surveillance; leaves open questions on polio monitoring reliability in unstable regions.
BACKGROUND: Since December 2012, the Central African Republic (CAR) has been undergoing a severe military and political conflict. This situation has resulted in general insecurity and total disorganization of surveillance activities, including those for acute flaccid paralysis (AFP). In this study, we used laboratory data to evaluate surveillance of AFP in 2013 and 2014, the most critical period of the conflict. METHODS: < .05 as the threshold for significance. RESULTS: Decreased activity of AFP surveillance of 57% was registered in 2013 and 36% in 2014 compared with previous years. Only 37.3% and 49.7% of children with AFP were vaccinated in 2013 and 2014, respectively, but no wild poliovirus or vaccine-derived poliovirus (VDPV) was isolated. Laboratory performance concerning the timeliness of cell culture and intratypic differentiation/VDPV results was only 65.5% and 66.7% of the target in 2013 but reached 95.5% and 100% in 2014. CONCLUSIONS: All personnel involved in the monitoring of AFP must be mobilized to improve vaccination coverage and surveillance activities in the CAR.
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Farra et al. (2017) conducted an observational in Acute flaccid paralysis (AFP) / Poliomyelitis. Military and political conflict (2013-2014) vs. Previous years (pre-conflict) was evaluated on Decrease in AFP surveillance activity. The 2013-2014 military and political conflict in the Central African Republic was associated with a 57% and 36% decrease in acute flaccid paralysis surveillance activity compared with previous years.
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