This case highlights the difficulty in diagnosing high-risk coronary artery anomalies, specifically acute angle take-off and ostial ridges, which can cause exercise-related sudden cardiac death in young athletes despite a negative initial cardiac workup.
Highlights diagnostic challenges of high-risk coronary anomalies in athletes despite negative workup; leaves open need for improved screening modalities.
Coronary artery anomalies are, after hypertrophic cardiomyopathy, the second most common cause of exercise-related sudden cardiac death in young American athletes. These anomalies have been associated with myocardial ischemia, arrhythmia, and sudden death during exercise. A 14-yr-old male with no previous abnormal medical history collapsed during soccer practice and was successfully resuscitated without defibrillation. An extensive cardiac workup did not reveal any abnormalities. Two weeks later, he experienced a cardiac arrest while running and could not be resuscitated. Autopsy demonstrated an acute angle take-off of the left main coronary artery and a transverse slit-like opening with a fibrous cushion, which created a kink near its origin. This case report illustrates the difficulty in diagnosing coronary artery anomalies in general, and acute angle take-off and ostial ridges in particular.
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ISKANDAR et al. (2004) studied this question.
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