Preclinical study demonstrates acoustic monitoring tracks liposome delivery across the blood-brain barrier, indicating scalable real-time assessment during ultrasound therapy.
. Passive acoustic detection during treatments revealed a correlation between acoustic signal and MRI contrast, providing a scalable metric for assessing clinical treatment efficacy in real-time. In conclusion, therapeutic ultrasound exposure can enhance delivery of large trackable nanoparticles into the brain, while enabling real-time treatment monitoring and verification.
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Payne et al. (2024) studied this question.
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