Why the study?
Does the double indicator-dilution method accurately estimate the amount of mitral regurgitation compared to usual clinical and catheterization criteria?
Does the double indicator-dilution method accurately estimate the amount of mitral regurgitation compared to usual clinical and catheterization criteria?
The double indicator-dilution method correlates well with standard clinical and catheterization criteria for estimating mitral regurgitation severity.
Supports indicator-dilution validation in mitral regurgitation; leaves open prospective confirmation before clinical adoption.
The amount of mitral regurgitation was estimated in 50 patients by an indicator-dilution technic and by the usual clinical, catheterization, operative, and autopsy criteria. There was a good correlation between the two estimates. Patients with significant mitral regurgitation (grade 2 or grade 3) had, with one exception, Q R / Q F ratios above 0.41. There were at least two instances where the calculated Q R / Q F was almost certainly falsely high. It seems likely that these discrepancies are related to the presence of an unusually large volume between the pulmonary artery and the femoral artery.
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Wilson et al. (1961) studied this question.
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