Key result
Traumatic head injury (OR 16-29) and autologous salvaged blood (OR 24; 95% CI 2.5-237) were associated with an increased risk of disseminated intravascular coagulation after primary craniotomy.
Why the study?
What is the incidence and mortality of disseminated intravascular coagulation (DIC) after primary craniotomy?
Population
3,164 patients who underwent primary craniotomy at Mayo Clinic Rochester between January 1, 2000 and…
Design
Cohort
Follow-up
72 hours
Authors
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May warrant closer DIC monitoring in traumatic head injury craniotomy cases; hypothesis-generating and requires prospective validation before guiding transfusion practice.
Cohort (n=3,164)
No
What is the incidence and mortality of disseminated intravascular coagulation (DIC) after primary craniotomy?
Odds Ratio: 24 (95% CI 2.5–237)
DIC is a rare but highly fatal complication after primary craniotomy, with traumatic head injury being a significant risk factor.
Pasternak et al. (2008) conducted a cohort in Primary craniotomy (n=3,164). Autologous salvaged blood vs. No autologous salvaged blood was evaluated on Development of disseminated intravascular coagulation (DIC) (OR 24, 95% CI 2.5-237). Traumatic head injury (OR 16-29) and autologous salvaged blood (OR 24; 95% CI 2.5-237) were associated with an increased risk of disseminated intravascular coagulation after primary craniotomy.
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