Wearable OLED-OPDMedical Devices for Blood GlucoseManagement: From Diagnosis to Treatment

Diabetes mellitus remains a critical global health challenge. While optical technologies offer noninvasive alternatives to painful diagnostics, traditional wearable sources such as LEDs face limitations in flexibility and thermal stability. In this study, we propose a fully integrated, flexible organic optoelectronic platform combining organic light-emitting diodes (OLEDs) and organic photodiodes (OPDs) for simultaneous hyperglycemia management. To optimize therapeutic efficacy, we first identified the ideal wavelength for glucose regulation via photobiomodulation (PBM) on HaCaT cells. Leveraging these results, we developed a skin-attachable patch featuring a stable, low-heat OLED module and an OPD. This platform enables real-time monitoring of photoplethysmography (PPG) and its second derivative, accelerated photoplethysmography (APG). PPG is used for short-term monitoring, such as blood glucose elevation, while APG is used for long-term monitoring, such as arterial stiffness and vascular aging. Simultaneously, the integrated red OLED delivers targeted PBM therapy to effectively control the glucose levels. This dual-functional organic platform represents a significant advancement in patient-centered, proactive diabetes management, offering a practical solution for continuous monitoring and treatment in daily life.