Why the study?
Does a prototype prosthetic myocardium improve hemodynamic parameters in a canine model of congestive failure following left ventricular infarction and excision?
Population
11 dogs in congestive failure after 17 ± 1.1% of the left ventricle was infarcted and excised under…
Comparison
Implantation and activation of a prototype… vs Device turned 'off'
Design
Preclinical
Authors
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Hypothesis-generating for prosthetic myocardium in post-infarct failure; human studies required before clinical translation.
Does a prototype prosthetic myocardium improve hemodynamic parameters in a canine model of congestive failure following left ventricular infarction and excision?
A prototype prosthetic myocardium significantly improved hemodynamic parameters in a canine model of congestive heart failure following massive left ventricular infarction and excision.
Kikuchi et al. (1980) studied this question.
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