Key result
Statistical assessments of diaphragm muscle EMG activity stationarity in awake rats characterized three phases of neuromotor control: motor unit recruitment, sustained activity, and derecruitment.
The findings provide novel insights into the temporal aspects of diaphragm neuromotor control and descending respiratory drive in unanesthetized animals.
Preclinical rat findings on diaphragm control require human validation before any clinical use; extends basic neuromotor insights to awake models.
We characterized three phases of neuromotor control-motor unit recruitment, sustained activity, and derecruitment-based on statistical assessments of stationarity of the diaphragm muscle (DIAm) EMG activity in awake rats. Our findings may allow indirect estimates of the contribution of motor unit recruitment and frequency coding toward generating force and provide novel insights about the temporal aspects of DIAm neuromotor control and descending respiratory drive in unanesthetized animals.
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Khurram et al. (2023) studied Spontaneous quiet breathing. Assessment of diaphragm muscle EMG activity stationarity was evaluated on Phases of neuromotor control (motor unit recruitment, sustained activity, and derecruitment). Statistical assessments of diaphragm muscle EMG activity stationarity in awake rats characterized three phases of neuromotor control: motor unit recruitment, sustained activity, and derecruitment.
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