Key result
Long-term reproducibility of nocturnal dipping was more stable when expressed as a continuous variable (intraclass correlation coefficient = 0.60) than as a dichotomous classification (kappa = 0.29).
Why the study?
Is nocturnal dipping more reproducible in the long term when expressed as a continuous variable compared to a dichotomous variable in never-treated patients?
Population
512 never-treated patients with two ambulatory blood pressure monitor assessments from a database of…
Comparison
Assessment of nocturnal dipping as a continuous… vs Assessment of nocturnal dipping as a dichotomous…
Design
Cohort
Follow-up
mean 29 (+/-19) months between assessments
Authors
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Continuous nocturnal dipping shows moderate reproducibility; leaves open whether it improves risk stratification over categorical status in untreated patients.
Observational (n=512)
Is nocturnal dipping more reproducible in the long term when expressed as a continuous variable compared to a dichotomous variable in never-treated patients?
Effect estimate: ICC 0.60 for continuous; kappa 0.29 for dichotomous
Nocturnal blood pressure dipping is more reproducible over the long term when expressed as a continuous rather than a dichotomous variable, suggesting it should be used continuously for cardiovascular risk stratification.
McGowan et al. (2009) conducted an observational in Blood pressure monitoring (n=512). Nocturnal dipping was evaluated on Long-term reproducibility of nocturnal dipping (ICC 0.60 for continuous; kappa 0.29 for dichotomous). Long-term reproducibility of nocturnal dipping was more stable when expressed as a continuous variable (intraclass correlation coefficient = 0.60) than as a dichotomous classification (kappa = 0.29).
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