Effects of Banxiaxiexin decoction on the intestinal microorganisms and enzyme activities in mice with spleendeficiency constipation

Introduction Constipation is a common gastrointestinal complaint clinically [1,2], affecting an estimated 27% of global population [3]. From the perspective of traditional Chinese medicine, constipation is relation to the dysfunction of large intestine. The disharmony between the spleen, stomach, liver and kidney is also concerned with constipation [4]. The intestine of