Key result
Immunosuppressive treatment with cyclophosphamide and prednisolone led to significant improvement of cardiac function in a 68-year-old woman with polyarteritis nodosa-induced heart failure.
Why the study?
Does immunosuppressive treatment improve cardiac function in a patient with heart failure due to polyarteritis nodosa-associated myocarditis?
Population
A 68-year-old woman with congestive heart failure and polyarteritis nodosa
Design
Case report
Authors
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Rare biopsy-proven myocarditis with vasculitis in PAN; leaves open prevalence and TLR-4 role in systemic disease.
Case Report (n=1)
Does immunosuppressive treatment improve cardiac function in a patient with heart failure due to polyarteritis nodosa-associated myocarditis?
Polyarteritis nodosa can present as unexplained heart failure due to myocarditis and intramural vasculitis, which is treatable with tailored immunosuppressive therapy.
Chimenti et al. (2020) conducted a case report in Polyarteritis nodosa with congestive heart failure (n=1). Immunosuppressive treatment (cyclophosphamide and prednisolone) was evaluated on Improvement of cardiac function. Immunosuppressive treatment with cyclophosphamide and prednisolone led to significant improvement of cardiac function in a 68-year-old woman with polyarteritis nodosa-induced heart failure.