Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 22, 1997Proceedings of the National Academy of SciencesOpen Access

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth

View Full Paper
Ask AI
Bookmark
Share

Authors

PMPatrick H. MaxwellQueen's University BelfastGDGabi U. DachsCancer Society of New ZealandJGJonathan GleadleFlinders University

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Maxwell et al. (1997) studied this question.

synapsesocial.com/papers/6a74b79a8d2049c8dd033719https://doi.org/10.1073/pnas.94.15.8104
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Nuclear Factor Induced by Hypoxia via De Novo Protein Synthesis Binds to the Human Erythropoietin Gene Enhancer at a Site Required for Transcriptional Activation1992 · 932 citations
  2. 2F4/80, a monoclonal antibody directed specifically against the mouse macrophage1981 · 1,615 citations
  3. 3Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.1993 · 417 citations
  4. 4Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis.1995 · 601 citations
  5. 5Post-transcriptional Regulation of Vascular Endothelial Growth Factor by Hypoxia1996 · 633 citations