Why the study?
Is renal hyperfiltration associated with increased arterial stiffness in adults with intermediate cardiovascular risk?
Cross-Sectional (n=2,251)
Yes
Is renal hyperfiltration associated with increased arterial stiffness in adults with intermediate cardiovascular risk?
Renal hyperfiltration is associated with elevated pulse pressure, suggesting it may be an early indicator of arterial stiffness in adults with intermediate cardiovascular risk.
Answers are grounded in this paper and cite their sources.
Reduced eGFR may increase arterial stiffness and CVD risk; leaves open targeted prevention strategies in CKD.
There is evidence that the reduction in estimated glomerular filtration rate (eGFR) increases the risk of arterial stiffness and cardiovascular disease (CVD) [1,2], and that CVD is the major cause of morbidity and mortality in subjects with decreased eGFR [3,4].
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Manuel A. Gómez‐Marcos (2019) conducted a cross-sectional in Intermediate cardiovascular risk (n=2,251). Renal hyperfiltration (RHF) vs. Non-renal hyperfiltration was evaluated on Elevated pulse pressure (PP ≥ 60.87 mmHg) (OR 1.47, 95% CI 1.15-1.89, p=0.003).
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