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February 1, 1987European Journal of BiochemistryOpen Access

Massive overproduction of dihydrofolate reductase in bacteria as a response to the use of trimethoprim

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Authors

JFJohn FlensburgOSOla Sköld

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Cite This Study

Flensburg et al. (1987) studied this question.

synapsesocial.com/papers/6a74bb75756843cacbb1d004https://doi.org/10.1111/j.1432-1033.1987.tb10664.x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dihydrofolate Reductase: X-ray Structure of the Binary Complex with Methotrexate1977 · 325 citations
  2. 2Codon usage in bacteria: correlation with gene expressivity1982 · 1,283 citations
  3. 3Nucleotide sequence of the E. coli gene coding for dihydrofolate reductase1980 · 376 citations
  4. 4Regulatory changes in the formation of chromosomal dihydrofolate reductase causing resistance to trimethoprim1984 · 13 citations