Key result
A modernized U-shaped wire suture on titanium mesh padding reduced the rate of sternal dehiscence recurrence to 9% compared to 30% with standard steel surgical wire (p=0.04).
Why the study?
Does re-osteosynthesis with titanium nickelide staples or U-shaped wire suture on titanium mesh reduce sternal dehiscence recurrence compared to steel surgical wire in patients with poststernotomy mediastinitis?
Cohort (n=29)
No
Does re-osteosynthesis with titanium nickelide staples or U-shaped wire suture on titanium mesh reduce sternal dehiscence recurrence compared to steel surgical wire in patients with poststernotomy mediastinitis?
Absolute Event Rate: 9% vs 30%
p-value: p=0.04
In patients with poststernotomy mediastinitis, re-osteosynthesis using U-shaped wire sutures on titanium mesh or titanium nickelide staples significantly reduces the recurrence of sternal dehiscence compared to traditional steel wire closure.
May support modified sternal closure technique; hypothesis-generating and requires randomized confirmation before practice change.
Aim. Comparison of the efficacy of different sternal closure techniques for patients with poststernotomy mediastinitis. Methods. From 2011 till 2016 29 patients after cardiothoracic surgeries complicated by poststernotomy mediastinitis and sternal dehiscence were observed. Depending on the used technique of re-osteosynthesis the patients were divided into 3 groups. In the group 1 re-osteosynthesis was performed with steel surgical wire, in group 2 - with titanium nickelide staples, and in group 3 - with developed by authors modernized U-shaped wire suture on the padding consisting of perforated metal sheet (titanium mesh). All patients during pre-operative period had vacuum wound drainage performed. In some patients during re-osteosynthesis vancomycin paste was used. Results. The rate of sternal dehiscence recurrence in the group 1 was 30%, in group 2 - 12.5% and in group 3 - 9% (р1-2=0.08, р1-3=0.04, р2-3=0.2). The average hospital stay in group 1 was 51 days, in group 2 - 27 days and in group 3 - 24 days (р1-2=0.05, р1-3=0.07, р2-3=0.4). In inharmed bone tissue of the sternum titanium nickelide staples use decreases the risk of recurrent sternal dehiscence by 17.5% compared to widely used osteosynthesis method with the use of steel wire. Conclusion. Osteosynthesis method suggested by the authors demonstrated its reliability in 91% of cases; use of vancomycin paste during re-osteosynthesis allowed avoiding recurrent wound infection both in short- and long-term periods in 100% of cases.
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Горбунов et al. (2017) conducted a cohort in Poststernotomy mediastinitis and sternal dehiscence (n=29). Modernized U-shaped wire suture on titanium mesh padding vs. Steel surgical wire was evaluated on Sternal dehiscence recurrence (p=0.04). A modernized U-shaped wire suture on titanium mesh padding reduced the rate of sternal dehiscence recurrence to 9% compared to 30% with standard steel surgical wire (p=0.04).
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