Key result
Baseline characteristics including higher comorbidities (OR 0.914; 95% CI 0.854-0.979) and physical inactivity (OR 0.707) were significant predictors of depression levels following cardiac rehab.
Why the study?
A prior history of depression before cardiac rehabilitation is linked to poor outcomes, but little is known about the factors determining the extent of benefit post-rehabilitation.
Observational (n=2,715)
Odds Ratio: 0.914 (95% CI 0.854–0.979)
In patients with comorbid depression undergoing cardiac rehabilitation, baseline characteristics including anxiety, comorbidities, physical inactivity, smoking status, and male gender are significant predictors of post-rehabilitation depression levels.
May guide targeted depression screening in cardiac rehab; leaves open whether modifying comorbidities or inactivity improves outcomes.
Background: A prior history of depression, at the point patients start cardiac rehabilitation (CR), is associated with poor outcomes; however, little is known about which factors play a part in determining the extent of benefit following CR. Therefore, we aim to identify and evaluate determinants of CR depression outcomes in patients with comorbid depression. Methods: test. A binary logistic regression was used to predict change in depression outcome following CR. Results: The analysis included 2715 CR participants with depression history. The determinants of Hospital Anxiety and Depression Scale (HADS) depression measurement post-CR were higher total number of comorbidities (OR 0.914, 95% CI 0.854 to 0.979), a higher HADS anxiety score (OR 0.883, 95% CI 0.851 to 0.917), physical inactivity (OR 0.707, 95% CI 0.514 to 0.971), not-smoking at baseline (OR 1.774, 95% CI 1.086 to 2.898) and male gender (OR 0.721, 95% CI 0.523 to 0.992). Conclusion: Baseline characteristics of patients with comorbid depression such as higher anxiety, higher total number of comorbidities, smoking, physical inactivity and male gender were predictors of their depression levels following CR. CR programmes need to be aware of comorbid depression and these related patient characteristics associated with better CR outcomes.
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Sever et al. (2019) conducted an observational in Comorbid depression in patients undergoing cardiac rehabilitation (n=2,715). Baseline characteristics (comorbidities, anxiety, physical inactivity, smoking status, gender) was evaluated on Hospital Anxiety and Depression Scale (HADS) depression measurement post-CR (OR 0.914, 95% CI 0.854 to 0.979). Baseline characteristics including higher comorbidities (OR 0.914; 95% CI 0.854-0.979) and physical inactivity (OR 0.707) were significant predictors of depression levels following cardiac rehab.
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