268Regional vascular wall stiffness in apparently healthy women and their mothers with arterial hypertension

Early markers disorders of vascular tone are a promising field of research as one of the mechanisms of arterial hypertension (AH). Purpose: To assess the state of regional vascular wall stiffness in apparently healthy women and their mothers with AH. Materials and methods: A total of 78 female first-degree relatives, of 39 families: 20 families - practically healthy mothers (Me 55,9 years [25%; 75%: 48,9; 68,5 years]) and healthy daughters (Me 29,3 years [25%; 75%: 22,0; 43,5 years]), and 19 families - mothers with hypertension stage I-II, 1–2 degrees (Me 60,6 years [25%; 75%:50,0; 71,0 years]) and their apparently healthy daughter (Me 36,0 years [25%; 75%:24,0; 46,0 years]), p<0,05. All underwent scanning of brachiocephalic arteries on the extracranial level; assessment of the thickness of the carotid intima-media (IMT) in manual and automatic modes (“Philips HD15”, USA). The cardio-ankle vascular index (CAVI) and ankle-brachial index (ABI) was determined by volume sphygmography (Vascular Screening System VaSera VS-1500N, Japan).