Why the study?
Does epidural anesthesia prolonged into the postoperative period reduce the incidence of deep venous thrombosis in patients undergoing knee arthroplasty compared to general anesthesia?
Does epidural anesthesia prolonged into the postoperative period reduce the incidence of deep venous thrombosis in patients undergoing knee arthroplasty compared to general anesthesia?
Epidural anesthesia prolonged into the postoperative period significantly reduces the risk of deep venous thrombosis following knee arthroplasty compared to general anesthesia.
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Supports prolonged epidural anesthesia to reduce DVT risk after knee arthroplasty; confirms benefit versus general anesthesia in this RCT.
Thirty-six patients scheduled for knee arthroplasty were randomized to general or epidural anesthesia that was prolonged into the postoperative period. All the patients wore graded compression stockings until full ambulation. No other thrombo-prophylactic treatment was given. In diagnosing deep venous thrombosis, bilateral ascending venography was performed 9-11 days after surgery. The incidence of thrombosis was 2/13 in the epidural group versus 10/16 in the general anesthesia group (P less than 0.05).
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Nielsen et al. (1990) studied this question.
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