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December 1, 1983Survey of Anesthesiology

Thromboembolism After Total Hip Replacement

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Why the study?

Does continuous epidural anesthesia reduce thromboembolism in patients undergoing total hip replacement compared to general anesthesia?

Population

60 patients undergoing total hip replacement

Comparison

Continuous epidural anesthesia vs General anesthesia

Design

RCT, randomly allotted

Authors

JMJ. MODIGUppsala University HospitalTBT. BorgUppsala University HospitalGMG. KARLSTR MUppsala University Hospital

Discussion

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Overview

Supports epidural preference over general anesthesia in total hip replacement to cut thromboembolism; confirms RCT benefit for regional techniques.

Structured PICO

Does continuous epidural anesthesia reduce thromboembolism in patients undergoing total hip replacement compared to general anesthesia?

P
Population
60 patients undergoing total hip replacement
I
Intervention
Continuous epidural anesthesia (0.5% bupivacaine with epinephrine intraoperatively; 0.25% bupivacaine with epinephrine every 3 h for 24 h postoperatively)
C
Comparator
General anesthesia (controlled ventilation with N2O-O2, intravenous fentanyl and pancuronium bromide; postoperative intramuscular narcotic analgesics on demand)
O
Outcome
Incidence of thromboembolism (deep venous thrombosis and pulmonary embolism)hard clinical

Continuous epidural anesthesia significantly reduces the risk of deep venous thrombosis and pulmonary embolism following total hip replacement compared to general anesthesia.

Cite This Study

MODIG et al. (1983) studied this question.

synapsesocial.com/papers/6a7444ca4e109b88a161adbdhttps://doi.org/10.1097/00132586-198312000-00056

Topics

Pulmonary embolism
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1EFFECTS OF EPIDURAL ANESTHESIA ON INCIDENCE OF VENOUS THROMBOEMBOLISM FOLLOWING JOINT REPLACEMENT1994 · 14 citations
  2. 2Factors Influencing Deep Vein Thrombosis Following Total Hip Arthroplasty Under Epidural Anesthesia1993 · 62 citations
  3. 3The prevalence of deep venous thrombosis after total hip arthroplasty with hypotensive epidural anesthesia.1994 · 104 citations
  4. 4Deep vein thrombosis after total hip replacement. A comparison between spinal and general anaesthesia1989 · 126 citations
  5. 5Comparison of General and Epidural Anesthesia in Patients Undergoing Primary Unilateral THR1997 · 36 citations