After an immune response, the body must eliminate the excess cells generated to fight the foreign invader. Recent work indicates that this removal occurs as a result of an intricate network of regulatory processes. In their Perspective, Boise and Thompson synthesize this new evidence for the control of lymphocyte number by proteases, Bcl-2-related proteins, cytokines, and adhesion factors.
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Boise et al. (1996) studied this question.
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