Key result
Type 1 diabetes without cardiovascular disease was associated with increased arterial stiffness compared to healthy controls in men (6.9 vs 6.3 m/s, P<0.001) and women (6.4 vs 6.0 m/s, P=0.023).
Why the study?
Is arterial stiffness increased in patients with type 1 diabetes without cardiovascular disease compared to healthy controls?
Case-Control (n=136)
Is arterial stiffness increased in patients with type 1 diabetes without cardiovascular disease compared to healthy controls?
Arterial stiffness is increased in patients with type 1 diabetes without clinical cardiovascular disease, and in men, this is independently associated with low-grade inflammation.
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May support early vascular monitoring in type 1 diabetes; hypothesis-generating for prognostic and therapeutic implications.
Llauradó et al. (2012) conducted a case-control in Type 1 diabetes without clinical cardiovascular disease (n=136). Type 1 diabetes vs. Healthy subjects was evaluated on Arterial stiffness assessed by aortic pulse wave velocity (aPWV). Type 1 diabetes without cardiovascular disease was associated with increased arterial stiffness compared to healthy controls in men (6.9 vs 6.3 m/s, P<0.001) and women (6.4 vs 6.0 m/s, P=0.023).
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