What question did this study set out to answer?

To assess the efficacy of catheter-directed radiofrequency ablation in treating severely symptomatic, drug-resistant benign ventricular arrhythmias.

May 1, 1992Pacing and Clinical Electrophysiology

Radiofrequency Ablation of Symptomatic but Benign Ventricular Arrhythmias

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Why the study?

Does radiofrequency ablation reduce ventricular ectopy in patients with severely symptomatic benign ventricular arrhythmias not responding to medical therapy?

Key Points

To assess the efficacy of catheter-directed radiofrequency ablation in treating severely symptomatic, drug-resistant benign ventricular arrhythmias.
Evaluated two patients (N=2) with severely symptomatic ventricular arrhythmias refractory to medical therapy using standard programmed stimulation protocols.
Advanced a 4-mm tip quadripolar ablation catheter percutaneously into the left ventricle (one case) or right ventricle (second case) to identify arrhythmogenic foci via pace mapping prior to radiofrequency current delivery.
Precise pace mapping permitted targeted radiofrequency energy delivery to the arrhythmogenic focus in both the left and right ventricular chambers.
Postablation ambulatory monitoring demonstrated virtual eradication of ventricular ectopy in both treated cases.

Structured PICO

Does radiofrequency ablation reduce ventricular ectopy in patients with severely symptomatic benign ventricular arrhythmias not responding to medical therapy?

Population

2 patients with severely symptomatic 'benign' ventricular arrhythmias not responding to medical therapy

Intervention

Radiofrequency ablation using a quadripolar ablation catheter with a 4-mm tip after precise pace mapping

Outcome

Ventricular ectopy on postablation ambulatory recordingsurrogate

Radiofrequency ablation offers an effective therapeutic alternative for severely symptomatic, medically refractory 'benign' ventricular arrhythmias.

Discussion

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Implication

May support ablation in refractory symptomatic ectopy; hypothesis-generating from this N=2 case report and requires prospective validation.

Cite This Study

Gürsoy et al. (1992) studied this question.

synapsesocial.com/papers/6a74d7351078cf7de2b1df40 https://doi.org/10.1111/j.1540-8159.1992.tb06839.x

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Implication

May support ablation in refractory symptomatic ectopy; hypothesis-generating from this N=2 case report and requires prospective validation.

Radiofrequency Ablation of Symptomatic but Benign Ventricular Arrhythmias

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Radiofrequency Ablation of Symptomatic but Benign Ventricular Arrhythmias

Key Points

Structured PICO

Discussion

Implication

Cite This Study

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