Why the study?
Does mechanical dispersion measured by speckle tracking echocardiography associate with the presence of nonsustained ventricular tachycardia in patients with hypertrophic cardiomyopathy?
Population
31 patients with hypertrophic cardiomyopathy caused by the Finnish founder mutation MYBPC3-Q1061X, and 20…
Comparison
Measurement of mechanical dispersion using… vs HCM patients without nonsustained ventricular…
Design
Cross-sectional
Follow-up
24 hours (ambulatory ECG monitoring)
Key result
Increased mechanical dispersion was independently associated with the presence of NSVT in patients with hypertrophic cardiomyopathy (OR 1.60; 95% CI 1.05-2.45; p=0.030).
Authors
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May inform NSVT risk stratification in HCM; hypothesis-generating and requires prospective validation.
Observational (n=51)
Does mechanical dispersion measured by speckle tracking echocardiography associate with the presence of nonsustained ventricular tachycardia in patients with hypertrophic cardiomyopathy?
Odds Ratio: 1.6 (95% CI 1.05–2.45)
p-value: p=0.030
Increased left ventricular mechanical dispersion measured by speckle tracking echocardiography is independently associated with nonsustained ventricular tachycardia in patients with hypertrophic cardiomyopathy, suggesting its potential utility in sudden cardiac death risk stratification.
Jalanko et al. (2016) conducted an observational in Hypertrophic cardiomyopathy (n=51). Mechanical dispersion measured by speckle tracking echocardiography vs. Lower mechanical dispersion was evaluated on Presence of nonsustained ventricular tachycardia (NSVT) on 24-h ambulatory ECG monitoring (OR 1.60, 95% CI 1.05-2.45, p=0.030). Increased mechanical dispersion was independently associated with the presence of NSVT in patients with hypertrophic cardiomyopathy (OR 1.60; 95% CI 1.05-2.45; p=0.030).