Key result
Point-of-care cardiac troponin I demonstrated an area under the curve of 0.833 for diagnosing acute coronary syndrome, with sensitivity improving to 83.3% when sampled more than 3 hours after symptom onset.
Why the study?
Does point-of-care cardiac troponin measurement accurately diagnose acute coronary syndrome in emergency department patients?
Population
1,449 patients whose cardiac troponin levels were measured in the emergency department using a POC system…
Design
Cohort
Authors
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May support later sampling for ACS diagnosis; leaves open prospective validation of point-of-care troponin performance.
Observational (n=1,449)
No
Does point-of-care cardiac troponin measurement accurately diagnose acute coronary syndrome in emergency department patients?
Absolute Event Rate: 0.833% vs 0.786%
Point-of-care cardiac troponin I is suitable for diagnosing acute coronary syndrome when sampled >3 hours after symptom onset, but requires careful interpretation if sampled earlier due to lower sensitivity.
Suzuki et al. (2018) conducted an observational in Acute coronary syndrome (n=1,449). Point-of-care cardiac troponin I measurement vs. Point-of-care cardiac troponin T measurement was evaluated on Area under the receiver operating characteristic curve (AUC) for diagnosing acute coronary syndrome. Point-of-care cardiac troponin I demonstrated an area under the curve of 0.833 for diagnosing acute coronary syndrome, with sensitivity improving to 83.3% when sampled more than 3 hours after symptom onset.
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