Key result
In patients with Type II diabetes, the presence of microalbuminuria was associated with a significantly higher occurrence of retinopathy compared to those without microalbuminuria (52.2% vs 10.8%, p<0.05).
Cross-Sectional (n=60)
No
Absolute Event Rate: 52.17% vs 10.81%
p-value: p=<0.05
Microalbuminuria is significantly associated with the presence of retinopathy in patients with Type II diabetes, highlighting its utility as an early marker for microvascular complications.
Supports retinopathy screening consideration in microalbuminuric Type 2 diabetes; hypothesis-generating and requires prospective confirmation.
Background & Objective: Diabetes Mellitus has become a major health problem in India & it has been estimated that the burden of Type 2DM is projected to increase to 87 million by 2030. Diabetic microvascular complications are retinopathy, nephropathy & neuropathy leads to morbidity & mortality. Microalbuminuria is associated with diabetic retinopathy in Type2DM patients and is a reliable marker of retinopathy. The demonstrated relationship between proteinuria and the development of retinopathy and nephropathy in type1 diabetes makes this an important issue to be studied in much more common type2 diabetes too. Materials & Methods: The study group comprised of diagnosed 60 Type II diabetes mellitus randomly selected patients within the age group of 40 -60 years. After taking informed consent from each patient, complete clinical details & systemic examinations were noted. 24 hours urine sample was obtained for detection of microalbuminuria & macroalbuminuria, presence or absence of retinopathy was detected with the help of ophthalmologist among all study group patients. Statistics: The results obtained were analyzed by chi-square test. p-value<0.05 considered as statistically significant. Results: Microalbuminuria was present in 23 patients represented a 38.33% rate of occurrence and Retinopathy was present in 16 patients represented 26.67% rate of occurrence. Subjects with microalbuminuria showed significantly higher occurrence of retinopathy as compared to subjects without microlabuminuria (p<0.05). Conclusion: Microalbuminuria is the best documented predictor of diabetic nephropathy and is associated with retinopathy in Type II diabetic patients. Regular screening with microalbuminuria & retinopathy will prevent from further worsening of diabetes related complications.
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Dr Naveen. P (2018) conducted a cross-sectional in Type II diabetes mellitus (n=60). Microalbuminuria vs. Without microalbuminuria was evaluated on Occurrence of retinopathy (p=<0.05). In patients with Type II diabetes, the presence of microalbuminuria was associated with a significantly higher occurrence of retinopathy compared to those without microalbuminuria (52.2% vs 10.8%, p<0.05).
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