Key result
Intraosseous administration of adenosine at increasing doses was unsuccessful in converting supraventricular tachycardia in two pediatric patients.
Why the study?
Does intraosseous adenosine administration successfully convert supraventricular tachycardia in pediatric patients?
Case Report (n=2)
Does intraosseous adenosine administration successfully convert supraventricular tachycardia in pediatric patients?
Intraosseous administration of adenosine appears to be an unreliable method for converting supraventricular tachycardia in pediatric patients.
Caution advised with intraosseous adenosine for pediatric SVT; hypothesis-generating and requires prospective validation.
Supraventricular tachycardia (SVT) is a common tachyarrhythmia in the pediatric population that can necessitate immediate treatment. Adenosine has been well studied as a mainstay treatment, but the methods of adenosine administration have not been very well delineated. The intraosseous technique has presented itself as a possible method of administration. We describe 2 cases in which adenosine was administered through bone marrow infusion to convert SVT without success. The cases we describe show that intraosseous is not a reliable method of administering adenosine to stop SVT. Both patients presented with SVT refractory to vagal maneuvers and difficult intravenous placement. Intraosseous access was achieved, but administration of adenosine at increasing doses was unable to successfully convert the arrhythmia.
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Goodman et al. (2012) conducted a case report in Supraventricular tachycardia (SVT) (n=2). Intraosseous adenosine was evaluated on Conversion of SVT. Intraosseous administration of adenosine at increasing doses was unsuccessful in converting supraventricular tachycardia in two pediatric patients.
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