Key result
Emerging MRI techniques, including the central vein sign and susceptibility-weighted imaging, hold promise in improving the diagnosis, prediction, and disease monitoring of multiple sclerosis.
Why the study?
Conventional MRI sequences and measures currently used in clinical practice have limitations in diagnosis, predicting future disability, and monitoring disease activity in multiple sclerosis, especially progressive subtypes.
Do emerging MRI techniques improve diagnosis, prediction, and disease monitoring in multiple sclerosis compared to conventional MRI?
Do emerging MRI techniques improve diagnosis, prediction, and disease monitoring in multiple sclerosis compared to conventional MRI?
Novel MRI techniques may overcome the limitations of conventional MRI in accurately diagnosing and staging multiple sclerosis.
Emerging MRI measures may aid progressive MS diagnosis; leaves open validation before clinical adoption.
Magnetic resonance imaging (MRI) has revolutionized the diagnosis and management of people living with multiple sclerosis (MS). However, conventional MRI sequences and measures currently used in clinical practice have limitations in the appropriate diagnosis, prediction of future disability, and monitoring of disease activity in MS. A specific challenge is the accurate and timely diagnosis of progressive subtypes of MS. This article will summarize emerging MRI measures that may be of utility as clinical tools in diagnosis and prediction in MS. Although a wide range of MRI techniques have different strengths and weaknesses, those that will be discussed in this article include the "central vein sign," leptomeningeal inflammation/enhancement, conventional and quantitative spinal cord imaging, susceptibility-weighted imaging, and high-field MRI techniques. There are a number of novel and emerging MRI techniques that hold promise in improving diagnosis, prediction, and disease monitoring in MS.
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Oh et al. (2020) conducted a review in Multiple sclerosis. Emerging MRI techniques vs. Conventional MRI sequences was evaluated. Emerging MRI techniques, including the central vein sign and susceptibility-weighted imaging, hold promise in improving the diagnosis, prediction, and disease monitoring of multiple sclerosis.
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