Key result
Extracorporeal life support in pregnant and peripartum women resulted in a 64% maternal survival rate.
Why the study?
What are the outcomes and clinical challenges of extracorporeal life support in pregnancy and peripartum cases of collapse?
Observational (n=11)
No
What are the outcomes and clinical challenges of extracorporeal life support in pregnancy and peripartum cases of collapse?
Answers are grounded in this paper and cite their sources.
Extracorporeal life support in peripartum collapse is feasible and associated with a 64% maternal survival rate, providing cohort data to support its use despite unique challenges in managing cardiac output and anticoagulation.
The American Heart Association scientific statement on cardiac arrest in pregnancy did not endorse extracorporeal life support for lack of cohort data. We studied all pregnancy and peripartum cases of extracorporeal life support in 1 medical center (n = 11), including collapse due to infection (n = 6, 55%), thromboembolism (n = 3, 27%), and cardiac disease (n = 2, 18%). Half of the cases (n = 5, 45%) involved extracorporeal cardiopulmonary resuscitation. Most mothers survived (n = 7, 64% [95% confidence interval, 32%-88%]). Deaths were attributable to oxygenator blockage (n = 1) and late sepsis (n = 3). The 2 unique clinical challenges were maintenance of high peripartum cardiac outputs and balancing anticoagulation with hemostasis.
No takes yet. Share an insight, caveat, or question.
Biderman et al. (2017) conducted an observational in Cardiac arrest or collapse in pregnancy and peripartum (n=11). Extracorporeal life support was evaluated on Maternal survival (95% CI 32%-88%). Extracorporeal life support in pregnant and peripartum women resulted in a 64% maternal survival rate.
Synapse has enriched 10 related papers. Consider them for comparative context: