Answers are grounded in this paper and cite their sources.
The propositus in a Black family has elevated Hb-F and approximately equal amounts of Hb-A and Hb-S. Hematological and chemical studies of the propositus and his family show elevated Hb-F in the father and a sibling and sickle cell trait in the mother and another sibling. This family is believed to have a form of the hereditary persistence of fetal hemoglobin in which beta chains are produced in cis to the determinant.
No takes yet. Share an insight, caveat, or question.
Altay et al. (1976) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: