Why the study?
Does chemotherapy without irradiation affect final height in children with acute lymphoblastic leukemia?
Population
28 children treated for acute lymphoblastic leukemia without irradiation, median age at diagnosis 4.4 years.
Design
Cohort
Follow-up
Until final height was reached (in 22 patients)
Authors
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May reassure on final height after chemo-only ALL therapy; hypothesis-generating and leaves generalizability open.
Does chemotherapy without irradiation affect final height in children with acute lymphoblastic leukemia?
Children treated for acute lymphoblastic leukemia with chemotherapy alone experience catch-up growth resulting in normal final height and body proportions.
Holm et al. (1994) studied this question.
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