Why the study?
Does non-invasive cardiac imaging improve patient selection for cardiac resynchronization therapy in patients with advanced heart failure?
Does non-invasive cardiac imaging improve patient selection for cardiac resynchronization therapy in patients with advanced heart failure?
Non-invasive imaging to assess mechanical dyssynchrony, scar burden, and venous anatomy may improve patient selection and response rates for cardiac resynchronization therapy.
May aid CRT selection in advanced HF; leaves open need for randomized trials before practice change.
Cardiac resynchronization therapy (CRT) is an established therapy for patients with advanced heart failure, depressed left ventricular (LV) function and wide QRS complex. A substantial amount of patients do not respond to CRT. Recent studies suggest that assessment of mechanical dyssynchrony may allow identification of potential CRT responders. In addition, presence of scar tissue and venous anatomy may play a role in the selection of candidates. This article summarizes the role of non-invasive cardiac imaging modalities addressing these issues in the selection of CRT candidates.
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Veire et al. (2009) studied this question.
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