What question did this study set out to answer?

To clarify the clinical, radiologic, and pathologic features of brainstem infarction associated with large fusiform vertebrobasilar aneurysms.

January 1, 1989Neurology

Stroke in patients with fusiform vertebrobasilar aneurysms

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Authors

MPMichael S. PessinBoston University MCMarc I. ChimowitzRutgers, The State University of New Jersey SLSteven R. LevineVascular / Pulmonary Vascular

Discussion

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Implication

Case series reveals distinct ischemic stroke mechanisms and outcomes in patients with fusiform vertebrobasilar aneurysms, highlighting risks of arterial occlusion and rupture.

Key Points

To clarify the clinical, radiologic, and pathologic features of brainstem infarction associated with large fusiform vertebrobasilar aneurysms.
Clinical, radiologic (angiography and computed tomography), and pathologic evaluation of seven patients (N=7) presenting with brainstem infarction and large fusiform vertebrobasilar aneurysms.
Postmortem autopsy examinations performed on two patients to identify vascular and parenchymal mechanisms of tissue injury.
Angiography and CT revealed fusiform dilation across all cases, accompanied by intraluminal thrombi in four patients and severe basilar artery stenosis in one.
Two distinct clinical courses emerged: unilateral pontine infarcts with favorable outcomes due to penetrating artery obstruction, and fatal bilateral pontine infarcts resulting from complete basilar artery occlusion.
Autopsy confirmed mechanisms including local arterial thrombosis, distal embolization causing hemorrhagic infarction, and fatal aneurysmal rupture producing subarachnoid hemorrhage.

Cite This Study

Pessin et al. (1989) studied this question.

synapsesocial.com/papers/6a7524891646b2abe503554f https://doi.org/10.1212/wnl.39.1.16

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Implication

Case series reveals distinct ischemic stroke mechanisms and outcomes in patients with fusiform vertebrobasilar aneurysms, highlighting risks of arterial occlusion and rupture.

Stroke in patients with fusiform vertebrobasilar aneurysms

Discussion

Member takes

Implication

Key Points

Cite This Study

Stroke in patients with fusiform vertebrobasilar aneurysms

Discussion

Member takes

Implication

Key Points

Cite This Study

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