Why the study?
Right ventricular apical pacing may impair left ventricular function, but whether right ventricular non-apical pacing provides beneficial effects as an alternative remains unknown.
Does right ventricular non-apical pacing improve left ventricular function compared to right ventricular apical pacing in patients with pacemakers?
Population
1246 patients with pacemakers across 10 studies
Comparison
Right ventricular non-apical pacing vs right ventricular apical pacing
Design
Systematic review and meta-analysis of randomized controlled trials and retrospective cohort studies
Authors
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Favors right ventricular non-apical over apical pacing to preserve LVEF; confirms mid- and long-term benefits from randomized evidence.
Does right ventricular non-apical pacing improve left ventricular function compared to right ventricular apical pacing in patients with pacemakers?
Right ventricular non-apical pacing provides significant beneficial effects on postoperative left ventricular ejection fraction compared to right ventricular apical pacing in patients with a pacemaker implanted for more than 1 year.
Wu et al. (2024) studied this question.