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February 25, 2013Pacing and Clinical Electrophysiology46 citations

Effects of Right Ventricular Nonapical Pacing on Cardiac Function: A Meta‐analysis of Randomized Controlled Trials

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Why the study?

Does right ventricular nonapical pacing improve left ventricular ejection fraction compared to right ventricular apical pacing in patients requiring pacing?

Population

1,114 patients from 20 RCTs requiring right ventricular pacing

Comparison

Right ventricular nonapical pacing vs Right ventricular apical (RVA) pacing

Design

Meta-analysis

Follow-up

≥2 months

Authors

WWWANG WEIZONGZWZhongsu WangMGMei Gao

Discussion

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Overview

May support preferring RVNA over RVA pacing to preserve LVEF; extends trial data via meta-analysis.

Structured PICO

Does right ventricular nonapical pacing improve left ventricular ejection fraction compared to right ventricular apical pacing in patients requiring pacing?

P
Population
1,114 patients from 20 RCTs requiring right ventricular pacing
I
Intervention
Right ventricular nonapical (RVNA) pacing (mainly right ventricular septum [RVS])
C
Comparator
Right ventricular apical (RVA) pacing
O
Outcome
Left ventricular ejection fraction (LVEF) at the end of follow-upsurrogate

Right ventricular nonapical pacing, particularly septal pacing, improves left ventricular ejection fraction and interventricular synchrony compared to traditional apical pacing.

Cite This Study

WEIZONG et al. (2013) studied this question.

synapsesocial.com/papers/6a800c276085685ad346f705https://doi.org/10.1111/pace.12112
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