Why the study?
Outpatient treatment of low-risk acute pulmonary embolism might reduce hospitalisations, lower costs, and improve quality of life compared with inpatient care, but its effects required systematic assessment.
Does outpatient treatment improve outcomes or reduce mortality compared to inpatient treatment in adults with low-risk acute pulmonary embolism?
Does outpatient treatment improve outcomes or reduce mortality compared to inpatient treatment in adults with low-risk acute pulmonary embolism?
Low-certainty evidence from two RCTs shows no clear difference in mortality, bleeding, or PE recurrence between outpatient and inpatient treatment for low-risk acute PE.
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No clear safety difference supports outpatient care for selected low-risk PE; extends limited RCT data but leaves open need for larger trials.
Yoo et al. (2022) studied this question.