Why the study?
Most influenza A (H1N1) infections are mild, but hemodynamic instability requiring vasoactive drugs and ventilatory support is unusual.
H1N1 influenza can cause fulminant myocarditis leading to refractory cardiogenic shock and death in young, healthy individuals despite aggressive mechanical circulatory support.
Supports vigilance for cardiac complications in severe H1N1; leaves open need for prospective screening studies.
Influenza infection is a known cause of global morbidity and mortality. Most cases of influenza A (H1N1) influenza infection are mild and do not require hospitalization. Although the most common presentation is with upper respiratory tract symptoms, hemodynamic instability requiring vasoactive drugs and ventilatory support use is unusual. We present a case of acute fulminant myocarditis that presented with dyspnea, which was confirmed with laboratory tests, chest X-ray, and echocardiogram. The test for H1N1 in nasopharyngeal secretions was positive. The patient evolved to refractory cardiogenic shock despite the clinical measures applied.
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Hamoudi et al. (2019) studied this question.
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