May 1, 1996JAMA

Development of Cardiomyopathy in Female Carriers of Duchenne and Becker Muscular Dystrophies

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Population

197 women and girls aged 5 to 60 years ascertained to be carriers of the Duchenne muscular dystrophy or…

Design

Cohort

Follow-up

minimum of 3 to a maximum of 10 years

Authors

LPLuisa PolitanoUniversity of Campania "Luigi Vanvitelli"

Discussion

Member takes

Implication

Supports cardiac screening in female DMD/BMD carriers; extends observational data on age-related progression.

Structured PICO

Population

197 women and girls aged 5 to 60 years ascertained to be carriers of the Duchenne muscular dystrophy (DMD, n = 152) or Becker muscular dystrophy (BMD, n = 45) gene.

Outcome

Cardiac status at yearly examinations as determined by 12-lead electrocardiogram (ECG), 24-hour ambulatory ECG, M-mode and 2-dimensional echocardiography, carotid pulse tracing, and myocardial scintigram.surrogate

Female carriers of Duchenne and Becker muscular dystrophies have a high prevalence of progressive myocardial damage that increases significantly with age.

Cite This Study

Luisa Politano (1996) studied this question.

synapsesocial.com/papers/6a7549cdb35e02fb1503442d https://doi.org/10.1001/jama.1996.03530410049032

Topics

Cardiomyopathy

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Development of Cardiomyopathy in Female Carriers of Duchenne and Becker Muscular Dystrophies

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Development of Cardiomyopathy in Female Carriers of Duchenne and Becker Muscular Dystrophies

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider