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March 17, 2007AJP Heart and Circulatory Physiology

Diastolic ventricular interactions in endurance-trained athletes during orthostatic stress

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Why the study?

Does endurance training alter right and left ventricular volume responses to cardiac loading and unloading in males?

Population

16 males, comprising 8 endurance-trained and 8 normally active

Comparison

Lower-body positive and negative pressures vs Normally active males

Design

Cross-sectional

Authors

BEBen T. EschDefence Research and Development CanadaJessica M. ScottJessica M. ScottCardio-OncologyMHMark J. HaykowskyHeart Failure / Cardiomyopathy

Discussion

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Implication

May indicate altered LV compliance in athletes during unloading but should not change practice; leaves open mechanisms and clinical relevance.

Structured PICO

Does endurance training alter right and left ventricular volume responses to cardiac loading and unloading in males?

P
Population
16 males, comprising 8 endurance-trained (Vo2max 65.4 +/- 5.7 ml.kg-1.min-1) and 8 normally active (Vo2max 45.1 +/- 6.0 ml.kg-1.min-1)
I
Intervention
Lower-body positive (0-60 mmHg) and negative (0 to -80 mmHg) pressures
C
Comparator
Normally active males
O
Outcome
Right ventricular (RV) cavity dimensions and left ventricular (LV) volumes assessed by echocardiographysurrogate

Endurance-trained athletes exhibit differential left ventricular volume responses to cardiac loading and unloading compared to normally active individuals, despite similar right ventricular responses, suggesting altered ventricular interactions or intrinsic compliance.

Cite This Study

Esch et al. (2007) studied this question.

synapsesocial.com/papers/6a75578184fffe492cdbdff4https://doi.org/10.1152/ajpheart.00928.2006
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Endurance athletes?? stroke volume does not plateau1994 · 259 citations
  2. 2Regulation of central blood volume and cardiac filling in endurance athletes1993 · 93 citations
  3. 3Physical fitness and cardiovascular regulation: mechanisms of orthostatic intolerance1991 · 123 citations
  4. 4Contribution of External Forces to Left Ventricular Diastolic Pressure: Implications for the Clinical Use of the Starling Law1995 · 127 citations
  5. 5Influence of right ventricular hemodynamics on left ventricular diastolic pressure-volume relations in man.1979 · 134 citations