Why the study?
Limited data exist on the prospective association between HDL function metrics and cardiovascular disease events in the general population.
Is baseline HDL-C efflux capacity associated with incident cardiovascular disease events in the general population?
Is baseline HDL-C efflux capacity associated with incident cardiovascular disease events in the general population?
Baseline HDL cholesterol efflux capacity is inversely associated with incident cardiovascular events in the general population, independent of HDL-C and apoA-I levels.
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CEC may refine primary prevention risk assessment beyond HDL-C; leaves open whether targeting efflux capacity reduces events.
Ebtehaj et al. (2019) studied this question.
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