Why the study?
Is low hepatic lipase activity associated with an increased extent of coronary artery disease?
Population
200 consecutive men undergoing elective coronary angiography, 40 controls with normal angiograms, and a…
Comparison
Low hepatic lipase (HL) activity vs High hepatic lipase activity and controls with…
Design
Cross-sectional
Authors
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May identify a novel CAD risk marker; leaves open causal role and therapeutic potential pending prospective validation.
Is low hepatic lipase activity associated with an increased extent of coronary artery disease?
Low hepatic lipase activity is independently associated with a greater extent of coronary artery disease, suggesting it may serve as a novel risk factor and potential therapeutic target.
Dugi et al. (2001) studied this question.