Why the study?
Does high-dose neuroleptic treatment differ in patient characteristics and effectiveness compared to regular-dose treatment in psychiatric patients?
Population
67 psychiatric patients at two large state hospitals (38 high-dose patients and 29 regular-dose patients)
Comparison
High-dose neuroleptic medication vs Regular-dose neuroleptic medication
Design
Case-control
Authors
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High-dose neuroleptics appear reserved for refractory cases; leaves open whether escalation improves outcomes in severe psychiatric illness.
Does high-dose neuroleptic treatment differ in patient characteristics and effectiveness compared to regular-dose treatment in psychiatric patients?
High-dose neuroleptic treatment is often prescribed to a subgroup of chronic, regressed, and violent patients despite a lack of clear evidence for its effectiveness.
Kunz et al. (1993) studied this question.
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