Population
23 normal subjects
Comparison
Analysis of heart rate versus heart period using… vs Awake versus sleep conditions
Design
Cross-sectional
Follow-up
24 hours
Authors
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Heart period-based nonlinear HRV analyses require mean period adjustment for wake-sleep comparisons; leaves open standardization of fractal and entropy metrics.
Studies using heart period measures should account for the effect of mean heart period when analyzing fractal dimension and approximate entropy, as sleep-awake differences vary between heart rate and heart period.
Yeragani et al. (1998) studied this question.
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