Plasma levels of endothelial protein C receptor respond to anticoagulant treatment

Patients treated with coumarin-type oral anticoagulants (n=55), patients treated with unfractionated heparin, healthy volunteers given warfarin for 8 days, and patients beginning treatment with warfarin for a thrombotic disorder (n=7), compared to healthy asymptomatic adult volunteers (n=200).

Anticoagulant treatment (coumarin-type oral anticoagulants, unfractionated heparin, or warfarin)

Healthy asymptomatic adult volunteers (no treatment) or pretreatment baseline

Plasma soluble endothelial protein C receptor (sEPCR) levelssurrogate